Inflammatory Bowel Disease (IBD) is a broad term used to describe a health condition both acute and chronic, non-infectious, unregulated inflammation of Intestinal mucosa and underlying tissues affecting any part of gastro-intestinal tract (G.I.T). Clinically based on the histological, pathological, endoscopic, diagnostic, and radiological findings & symptoms majority of the cases are grouped into either- Ulcerative Colitis (UC) or Crohn’s disease (CD) which are related polygenic13 diseases with distinct features listed in Table1. A minority (<=10%) of clinical cases are grouped into Indeterminate Colitis1 (IC), since they either lack or possess features of both UC and CD. Symptoms of intestinal inflammation2 include anemia, persistent diarrhea,
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Impact of IBD is far-reaching not only affecting the patient financially, reduced quality of life, and loss of employment opportunities, but also on healthcare facilities due frequent physician visits, hospitalizations, and surgeries. A 2012 impact report8 by Crohn’s and Colitis Foundation of Canada pegged the total financial impact of IBD for year 2012 at $2.8 billion which is a sum of $1.2 billion due to direct costs8 (includes prescription drugs, hospitalization, physician visits, outpatient care and other costs like lab tests, non-physician services), and $1.6 billion due to indirect costs8 (includes long term & short term work losses, out of pocket expenses, early retirement, premature death, impact on education, and caregivers work loss). Per patient financial impact8 of IBD in Canada was also estimated at $11,220. The incidence and prevalence rates have been rising steadily in developing nations along with
Impact of IBD is far-reaching not only affecting the patient financially, reduced quality of life, and loss of employment opportunities, but also on healthcare facilities due frequent physician visits, hospitalizations, and surgeries. A 2012 impact report8 by Crohn’s and Colitis Foundation of Canada pegged the total financial impact of IBD for year 2012 at $2.8 billion which is a sum of $1.2 billion due to direct costs8 (includes prescription drugs, hospitalization, physician visits, outpatient care and other costs like lab tests, non-physician services), and $1.6 billion due to indirect costs8 (includes long term & short term work losses, out of pocket expenses, early retirement, premature death, impact on education, and caregivers work loss). Per patient financial impact8 of IBD in Canada was also estimated at $11,220. The incidence and prevalence rates have been rising steadily in developing nations along with