Infant Weight And Adult Disease Essay

818 Words Nov 10th, 2014 4 Pages
Twin studies aid in strengthening the correlations between fetal environment, low birth weight, and adult disease. On average, twins have lower than average birth weight as they experience reduction in growth during their third trimester due to limitations in size of the uterus (Vagero & Leon, 1994). Research involving monozygous and dizygous twins has determined that the lighter twin was more likely to develop higher blood pressure and have increased cardiovascular disease risk (Baird, Osmond, MacGregor, Snieder, Hales, & Phillips, 2001). This information suggests that two individuals who experience the same intrauterine environment can have varying birth weights, and those birth weights correlate to a greater incidence of disease. Twin studies assist in determining that the Fetal Origins Hypotheses and DOHaD are valid hypotheses in understanding the correlation between lower birth weight and increased risk of adult disease.
After studying how fetal environment and various factors throughout life can lead to noncommunicable diseases as an adult, one must look at the proximate and ultimate explanations of disease to bridge the gap between low birth weight and adult disease. While the proximate explanation aims to answer the question, “how does low birth weight lead to adult disease?” the ultimate explanation wants to understand “why does low birth weight lead to adult disease?” Although these questions may appear similar, the proximate explanation utilizes biological and…

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