To improve the outcome of personalised medicine it is necessary to satisfy the urgent need for a broad program of creative approaches to collection and collation data in a Knowledge Network (1, 2) of databases that make molecular, medical, behavioural, and socio-economic data available in comprehensive digital form to scientists, health care workers, patients, and administrators. The Innovative Medicines Initiative (IMI) on big data for better outcomes programme has taken important steps in this direction. However, there is an added need to expand the understanding by prospectively adding data from clinical studies and results from best clinical practice. The accumulated results build a continuously growing base of knowledge and provide the
