Patients with diabetes may have narrowed arteries leads to lack of healthy blood flow so that no pulse can be found in the feet (ischemia) lead to ulceration which is called diabetic foot that occur in 15% of diabetic patients. Pressure from shoes, cuts, bruises, or any injury to the foot may go unnoticed are the main cause of developing ulcer that leads the risk of lower-extremity amputation. Nerve damage due to diabetes causes altered or complete loss of sensation in the foot or leg. Vascular disease is another major problem in diabetes especially affects very small blood vessels supplying the skin. Pedal pulse will be felt by the health care personnel because in this condition the arteries are not affected. Impaired wound healing is a frequent and very severe problem in patients with diabetes mellitus.
