The pathogen spores that get through wounded skin into tissues are transformed into bacilli, which synthesize the toxin into the surrounding necrotized tissue. The tetanus toxin is one of the most toxic substances with approximated human lethal dose of lesser than 2.5 ng per kg of body weight. The toxin immediately affects the central nervous system of the person causing spastic paralysis.
Tetanus immunity is exclusively defined by the levels of antibodies against the toxin. Antibodies levels determination against toxins is clinically employed as an immunization index of either someone or population by vaccines. The most common method of assessing the specific immunoglobulin against tetanus toxin is the in vivo toxin neutralization test. This
Tetanus immunity is exclusively defined by the levels of antibodies against the toxin. Antibodies levels determination against toxins is clinically employed as an immunization index of either someone or population by vaccines. The most common method of assessing the specific immunoglobulin against tetanus toxin is the in vivo toxin neutralization test. This