Il-10 Stimulatory Effects

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IL-10 applies both stimulatory and inhibitory effects on various cell types. The therapeutic capacity of IL-10 as an anti-inflammatory agent elucidates from its ability to inhibit the monocyte/macrophage. IL-10 has been shown in vitro to slow down LPS induced production of TNFα, IL-1, IL-6, IL-8, G-CSF, and GM-CSF . Subsequently, IL-10 produces various anti-inflammatory effects. T cell function is also managed by IL-10. The overall effects of IL-10 are to weaken a Th1 cellular response and strengthen a Th2 humoral response.

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