Idiopathic Addison Disease

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Addison disease is a rare primary adrenal insufficiency, or progressive anemia, affecting those between the ages of 30-60 years old, but has been known to manifest at any time. There is an autoimmune mechanism that works to destroy adrenal cortical cells. It is characterized by insufficient corticosteroid and mineralocorticoid synthesis with elevated levels of serum ACTH. Idiopathic Addison disease, or organ-specific autoimmune adrenalitis, is an organ specific autoimmune disease that causes adrenal atrophy. It allows for the production of immunocytes against specific antigens within the adrenocortical cells. The clinical manifestations of Addison disease are results of hypocortisolism and hypoaldosteronism. The patient will experience

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