I am a strong believer that life is a gift and it is the greatest teacher to oneself and nothing can be a better way to use it productively than the path of science. My journey started from all the way from undergraduate has been a mixture of learning from various interdisciplinary fields. The skills of experimenting and practice are the two elements of my faith which built the foundations of what I still cherish are the long hours in the laboratory of my mentor Professor P Rajeswara Rao.
The zeal and the practice to unlearn to discover something new have always kept me happy that I am a part of such colossal fraternity which changed our understanding of human life and health globally.
During my undergraduate (B.Pharm) days, I was evaluating …show more content…
But hard thought and smart work keep one going. In course of time, I learned laboratory skills which were important to evaluate the C6 cell lines [Grade III astrocytoma cell line].We followed the trail and evaluated NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells a protein complex) which controls the DNA transcription in most of the eukaryotic cells. This was the potential line of interest in understanding the aspects of tumor cell progression, drug resistance. Our results validate that pantoprazole inhibited C6 glioma cell proliferation and induced apoptosis relatively by subduing NF-κB signaling. Pantoprazole is already clinically used for peptic ulcer disease and reflux esophagitis, considering above observations it signifies that pantoprazole might play a vital role in chemotherapy and in view of its low cost, negligible toxicity and high efficacy it is possible to extend its clinical application to control Glioma progression. This was a good start to understanding the apoptotic mechanisms but during the course, I also understood that academia and industry are two disconnected entities in India. It was important to understand the pace at which the industry was developing the pipeline and addressing the unmet needs across the disease areas …show more content…
As I mentioned earlier it was important to know the dynamics of a multi-national company in the industry alongside learning to work in different situations and people from various cultures. As a writer, it was more than just writing a manuscript, every project was an experience where an efficient blueprint and plan from start to terminus was important. These skills sets made me confident to manage the whole plan and execution for the entire congress support for ERS 2015.I was also one of the writers for the GEM 3 (US based Glycopyrronium studies for Chronic Obstructive Pulmonary Disease) which was published just around the time when the Food and Drugs Authority approved the dual bronchodilator QVA149 and Glycopyrronium for Chronic Obstructive Pulmonary Disease (COPD) in the United States. Beyond all this, I developed my skills to multi-task various documents, plan and manage full projects and various other tools with good amount editing tools, understanding and
The zeal and the practice to unlearn to discover something new have always kept me happy that I am a part of such colossal fraternity which changed our understanding of human life and health globally.
During my undergraduate (B.Pharm) days, I was evaluating …show more content…
But hard thought and smart work keep one going. In course of time, I learned laboratory skills which were important to evaluate the C6 cell lines [Grade III astrocytoma cell line].We followed the trail and evaluated NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells a protein complex) which controls the DNA transcription in most of the eukaryotic cells. This was the potential line of interest in understanding the aspects of tumor cell progression, drug resistance. Our results validate that pantoprazole inhibited C6 glioma cell proliferation and induced apoptosis relatively by subduing NF-κB signaling. Pantoprazole is already clinically used for peptic ulcer disease and reflux esophagitis, considering above observations it signifies that pantoprazole might play a vital role in chemotherapy and in view of its low cost, negligible toxicity and high efficacy it is possible to extend its clinical application to control Glioma progression. This was a good start to understanding the apoptotic mechanisms but during the course, I also understood that academia and industry are two disconnected entities in India. It was important to understand the pace at which the industry was developing the pipeline and addressing the unmet needs across the disease areas …show more content…
As I mentioned earlier it was important to know the dynamics of a multi-national company in the industry alongside learning to work in different situations and people from various cultures. As a writer, it was more than just writing a manuscript, every project was an experience where an efficient blueprint and plan from start to terminus was important. These skills sets made me confident to manage the whole plan and execution for the entire congress support for ERS 2015.I was also one of the writers for the GEM 3 (US based Glycopyrronium studies for Chronic Obstructive Pulmonary Disease) which was published just around the time when the Food and Drugs Authority approved the dual bronchodilator QVA149 and Glycopyrronium for Chronic Obstructive Pulmonary Disease (COPD) in the United States. Beyond all this, I developed my skills to multi-task various documents, plan and manage full projects and various other tools with good amount editing tools, understanding and