I Am A Carrier For Certain Alleles For Transcription Factor 7

1365 Words Mar 31st, 2016 null Page
I would like to be genotyped to see if I am a carrier for certain alleles for Transcription Factor 7-Like 2 (TF7L2) gene and if my family is genetically susceptible to the diseases. In other words, I want to know which SNP and what genotype I hold. The reason behind my decision is that I know that T2D is caused by environment and genetics. Getting tested will help me take further actions if my results show that I have predisposition. Many factors contribute to type 2 diabetes, for example, obesity, lack of exercise, and nutrition. Recently, many studies have shown that genetics play an important role in the disease too. Those studies investigate the linkage between T2D and close members, for instance twins. Researchers have tried for many years to find methods that help target the predisposition. One method works on sequencing known genes that normally perform regular functions like insulin production and then compare them to T2D alleles[2]. It helps find the proportion of people under study who actually have the disease and share the specific alleles. Another method called genome-wide linkage that would sequence specific genetic markers, for example, Transcription Factor 7-like 2(TF7L2) that is directly linked to the disease[2]. Having certain alleles of the disease means that someone is at higher risk of developing the diabetes. Within TF7L2 gene, there are three specific Single Nucleotide Polymorphism that showed strong connection to T2D[3]. These…

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