Hypermetabolism Essay

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Hypermetabolism is the physiological condition of increased rate of metabolic activity and is described by a strange increment in the body's basal metabolic rate. Hypermetabolism is caused by injury or multiple traumas to the body. This could be in the form of surgery, bone fractures, infections, burns and bone marrow transplant. Hypermetabolism is a symptom of hyperthyroidism which is characterised by an increment in the production of thyroid hormones hence an increase in the rate of cellular metabolism.
Bakhtyar et al, 2015 research on the occurrence of hypermetabolism in burn victims. It was found that hypermetabolism can persist up to 3 years after the trauma. They also reported that hypermetabolism plays an important part in the healing of severe burns in individuals. Hypermetabolism in burn victims occurs in two phases (Cuthberson et al., 2001), the first being 48-72 hours after the incident. There is initially a decrease in oxygen consumption and metabolic rate and then the second phase occurs within 5 days after being burnt. This is due to increased glycolysis, proteolysis, lipolysis and substrate cycling. As the body will be recovering from injuries from burns there is a need for degradation of damaged cells and the production of new cells to replace the damaged ones which will in turn cause the amount of
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However exercise stimulates the production of anti-inflammation cytokines. Exercise causes the increase in glucose uptake and an improvement in sensitivity of insulin (Peterson and Pederson, 2005). Exercise also enhances amino acid assimilation in the muscle tissue causing an increase in lean body mass as opposed to hypermetabolism where amino acids are being utilised for energy production via gluconeogenesis. Exercise maintains ATP levels in the body and metabolic demands are met and hence hypermetabolism is not necessary for energy

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