Prophylactic surgery is a risk-reducing surgery that includes prophylactic bilateral mastectomy (PBM), prophylactic contralateral mastectomy (PCM), and prophylactic bilateral salpingo-oophorectomy (PBSO). PBM is performed by removing 95% of the breast tissue and can reduce the risk of breast cancer by 95% (Hartmann et al, 2016). PCM can reduce the risk of breast cancer by 50% and ovarian cancer by 97%. PBSO removes both the breasts and ovaries, is performed laparoscopically - through small incisions that are minimally invasive - and can decrease the risk of death by HBOC by 75% (Meindl et al, 2011). Chemoprevention by use of tamoxifen is the only known option and decreases the risk of breast cancer by 38% in premenopausal women. Tamoxifen also decreases the chance of contracting contralateral great cancer by 50%. In terms of ovarian cancer, oral contraceptives have shown to decrease the risk of ovarian cancer by 50% and death by 80% (Nielsen et al,
Prophylactic surgery is a risk-reducing surgery that includes prophylactic bilateral mastectomy (PBM), prophylactic contralateral mastectomy (PCM), and prophylactic bilateral salpingo-oophorectomy (PBSO). PBM is performed by removing 95% of the breast tissue and can reduce the risk of breast cancer by 95% (Hartmann et al, 2016). PCM can reduce the risk of breast cancer by 50% and ovarian cancer by 97%. PBSO removes both the breasts and ovaries, is performed laparoscopically - through small incisions that are minimally invasive - and can decrease the risk of death by HBOC by 75% (Meindl et al, 2011). Chemoprevention by use of tamoxifen is the only known option and decreases the risk of breast cancer by 38% in premenopausal women. Tamoxifen also decreases the chance of contracting contralateral great cancer by 50%. In terms of ovarian cancer, oral contraceptives have shown to decrease the risk of ovarian cancer by 50% and death by 80% (Nielsen et al,