Anaphylactic reactions - The estimated incidence of anaphylaxis among vaccine recipients is 1.1 per million vaccine doses
(95% CI 0.1-3.9) (Bohkle et al., 2003).
Other safety issues
Despite numerous long-term studies, there is no evidence of serious adverse events that have been causally linked to hepatitis B vaccination. Several conditions that have been considered in the scientific literature are discussed below.
Neurological disease - There have been a number of severe neurological adverse events reported after hepatitis B vaccines and these primarily have included Guillain-Barré syndrome and multiple sclerosis (Shaw, 1988; Herroelen, 1991; Mahassin, 1993;
Trevisani, 1993; Nadler, 1993; Tartaglino, 1995, Mahoney et al., 1999). Establishing
(95% CI 0.1-3.9) (Bohkle et al., 2003).
Other safety issues
Despite numerous long-term studies, there is no evidence of serious adverse events that have been causally linked to hepatitis B vaccination. Several conditions that have been considered in the scientific literature are discussed below.
Neurological disease - There have been a number of severe neurological adverse events reported after hepatitis B vaccines and these primarily have included Guillain-Barré syndrome and multiple sclerosis (Shaw, 1988; Herroelen, 1991; Mahassin, 1993;
Trevisani, 1993; Nadler, 1993; Tartaglino, 1995, Mahoney et al., 1999). Establishing