Hemopoiesis Lab Report

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Q-1. Describe the function of hemoglobin in blood and describe how pH can affect the function of hemoglobin and the amount of oxygen in blood. Be sure to relate the lab results you obtained to this discussion.
Hemoglobin’s main function is to carry oxygen throughout the human body. As the oxygen molecule is dissolved in the blood it combines with hemoglobin forming oxyhemoglobin. Oxygen released from oxyhemoglobin increases as the blood pH levels decreases. Deoxyhemoglobin can also bind to the hydrogen ions to act as a buffer to minimize pH changes. In my results from the lab the graph shows that when the pressure is decreased oxygen binding to hemoglobin also decreases.

Q-2. Describe the process of hemopoiesis. Include where it occurs
…show more content…
Erythropoietin initiates the erythroblast stage that stimulate proerythroblasts to form erythroblasts. The formed erythroblast synthesizes hemoglobin and begins to shrink to a normoblast. The nucleus is then ejected from the normoblast forming a reticulocyte. When the reticulocyte enters the blood stream, the organelles contained begin to degenerate and is then considered a mature erythrocyte.
Thrombopoiesis produces the platelets and begins with a myeloid stem cell, which produces the progenitor cell when stimulated and becomes a megakaryoblast. The megakaryoblast responds to the hormone thrombopoietin and forms a megakaryocyte. The platelets are formed when small, membrane bound portions of cytoplasm break away.
Leukopoiesis is the formation of white blood cells. The myeloid cell line forms granulocytes and monocytes, which share a common stem cell. The stem cell is stimulated by CSFs to make myeloblast, which then creates promyelocytes. Eosinophilic myelocytes separate into eosinophils, basophilic myelocytes form basophils, and neutrophilic myelocytes develop into neutrophils. The lymphoid cell line creates lymphocytes and are involved in leukopoiesis. The stem cells break a part into B-lymphoblasts and T-lymphoblasts, which then mature and become B-lymphocytes and

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