Hemophilia Essay

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Hemophiliais an inherited bleeding disorder in which the blood does not clot normally due to a lack of clotting protein.
Children with hemophilia bleed for a longer time than others after an injury.
Hemophilia commonly is of two types –A and B (uncommon is haemophilia C).
There are various clotting factors in blood which are required for clotting of blood in the event of an injury. Deficiency of certain clotting factors can impair the clotting mechanism and increase the bleeding time.
Hemophilia A is deficiency of clotting Factor VIII in blood.
Hemophilia B is deficiency ofclotting factor IX in blood.
Both haemophilia A and B are X linked recessive disease. The incidence of haemophilia A is 1:5000 males and that of haemophilia B is 1:25000 males making haemophilia A much more common that hemohilia B. They affect all races equally.
Since haemophilia
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As children grow and become physically more active, symptoms may be observed in the form of swelling of a joint ( haemarthrosis), frequent bluish discoloration of the skin on mild injuries, prolonged bleeding from the oral cavity when teeth are erupting . Minor trauma in the oral cavity leading to prolonged bleeding may be seen. In children with the mild disease symptoms may only surface at the time of a surgery of tooth extraction.
Apart from the superficial bleeds , haemorrhage can also occur in the gastrointestinal system , genitourinary system, in the brain , which can impose a life threatening situation as well.
Treatment of haemophilia- The definitive treatment is injecting the deficient factor VIII which immediately stops bleeding. Other symptomatic management is also done by the doctors depending on the site and extent of

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