Glucosamine Sulfate Supplements: A Case Study

Brilliant Essays
7th November, 2014
Efficacy and safety comparisons between collagen derivatives and glucosamine sulfate supplements in treating adults with knee osteoarthritis.
Linh Nguyen (11916828). Evidence based practice. University of Technology, Sydney

I. CLINICAL SCENARIO
During my clinical placement, I have come across a scenario where a 40 year old woman came into the pharmacy, saying that she had recently diagnosed with knee osteoarthritis (KOA) and was looking for a good dietary supplement as suggested by her doctor. She has read some adverts online about how glucosamine sulfate (GS) and collagen can improve joint health by slowing down the joint breaking down, relieving the associated pain and stiffness and also reducing inflammation. She was
…show more content…
Hauser A. Ross: The Acceleration of Articular Cartilage Degeneration in Osteoarthritis by Nonsteroidal Anti-inflammatory Drugs. Journal of Prolotherapy. 2010, (2)1:305-322.
5. J.P.J. Van Vijven, P.A.J. Luijsterburg, A.P. Verhagen, G.J.V.M. van Osch, M. Kloppenburg, S.M.A. Bierma-Zeinstra: Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review. Osteoarthritis and Cartilage, 2012; 20(8):805-956.
6. James P Lugo, Zainulabedin M Saiyed, Francis C Lau, Jhanna Pamela L Molina, Michael N Pakdaman, Arya Nick Shamie and Jay K Udani: Undenatured type II collagen (UC-II®) for joint support: a randomized, double-blind, placebo-controlled study in healthy volunteers. Journal of the International Society of Sports Nutrition 2013, 10:48.
7. Deal CL, Moskowitz RW. Nutraceuticals as therapeutic agents in osteoarthritis. The role of glucosamine, chondroitin sulfate, and collagen hydrolysate. Rheum Dis Clin North Am. 1999; 25(2):379-95.
8. Ziad M. Hawamdeh, Jihad M. Al-Ajlouni. The Clinical Pattern of Knee Osteoarthritis in Jordan: A Hospital Based Study. Int J Med Sci 2013;
…show more content…
Kristine L. Clark: Nutritional Considerations in Joint Health. Clin Sports Med 26 (2007) 101–118.
10. Simon Wandel, Peter Jüni, Britta Tendal, Eveline Nüesch, Peter M Villiger, Nicky J Welton, Stephan Reichenbach, and Sven Trelle: Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010; 341:c4675.
11. Manninen P, Riihimäki H, Heliövaara M, Mäkelä P: Overweight, gender and knee osteoarthritis. International Journal of Obesity and Related Metabolic Disorders; Journal of the International Association for the Study of Obesity 1996, 20(6):595-597.
12. Steven Simoens, Gert Laekeman: Pharmacotherapeutic aspects of treating knee osteoarthritis with glucosamine sulphate. HEALTH 2010; Vol.2, No.7,

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