Giant Cell Tumors

Decent Essays
The most common bone tumors of the foot and ankle are osseous and cartilaginous lesions, including enchondromas, osteochondromas, and chondromyxoid fibromas [1]. Giant cell tumors
(GCT), chondroblastomas, osteoid osteomas, and osteoblastomas also occur. Non-neoplastic conditions include intraosseous lipomas, simple (unicameral) bone cysts, and aneurysmal bone cysts [2].
GCT, also known as osteoclastomas, are fairly common bone tumors, accounting for 5% of all primary bone tumors. They are benign tumors with a tendency for local aggressiveness and high rates of recurrence. The most common sites are the distal end of the femur, proximal end of the tibia, and distal end of the radius.
The foot is an unusual site for presentation of GCT, and GCT
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(M.A. Eid). and clinical signs are present. The presentation of GCT can be similar to that of giant cell reparative granulomas, brown tumors, and aneurysmal bone cysts [6].
Aneurysmal bone cysts are solitary benign osteolytic lesions.
Thirteen percent of aneurysmal bone cysts have been reported to occur around the ankle and in the foot. They can cause swelling and pain and can compromise the structural integrity of involved bone. Although the distal tibia and fibula are more common sites than the foot, aneurysmal bone cysts do occur in the tarsal bones.
Occasionally, aneurysmal bone cysts are completely solid [2].
Osteoblastomas are benign bone-forming neoplasms that most commonly present with pain. Approximately 9% involve the foot and ankle [7], with the neck of the talus being a common site. In the feet, they more commonly occur in cancellous bone; in other parts of the body, they more commonly occur in cortical bone.

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