Genetically The Human Genome Manipulation Essay

1204 Words Nov 8th, 2016 5 Pages
Genetically Modifying the Human Genome Genetically engineering the human genome, also known as the complete set of genetic material, is now more than just science fiction. After 25 years of collecting and analyzing scientific research, altering the human genome is becoming a concrete reality (Patrick Yu-Wai-Man). Genetically modifying the human genome is deliberately altering human genes for the purpose of producing offspring with those genetic changes. Understanding the history of genome engineering, knowing the procedures, and being aware of the ethical issues of this aggressive approach to curing human genetic diseases are the main aspects to grasping the whole knowledge of germline engineering on human embryos and gametes.

Human genome manipulation began in the 1980’s when discoveries of pronuclear microinjection exploded. In 1980 Jon Gordon, author of The Science and Ethics of Engineering the Human Germ Line, demonstrated that exogenous DNA, also known DNA that originates outside of the organism of study, could be introduced into the germline simply by the physical injection of a solution of cloned DNA into a zygote, also known as the diploid cell from the fusion of an ovum and a sperm cell (Kevin R Smith). After this landmark discovery from Jon Gordon, pronuclear microinjection, was the most widely accepted method of germline manipulation although it was outstandingly expensive (Kevin R Smith). The procedure of pronuclear microinjection consisted of filling a fine…

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