Genetic Personal Statement

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Having spent a substantial part of my year being there for a dear friend suffering from stage 4 colon cancer and seeing her condition worsen, my appreciation for the promising world of genetics has amplified. The need for more research on the molecular staging of cancer for example or the correlation between phenotype and the discrete genetic mutations present at a particular pre-malignant stage, will lead to more accurate prognosis, therapeutic intervention, and treatment targeted for a precise genetic profile. With these theories in mind, I am determined to pursue a career contributing to the personalization of healthcare, prediction of disease and its prevention.
With a BSc in Medical Genetics, I have grown with love and fascination for
…show more content…
My BSc has equipped me with many of skills that will help me excel in this MSc, from setting up experiments to statistical computing using the program “R” for example. In my final year, I was competitively allocated a project with both the Centre of Immunology and the Advanced Light Microscopy facility at the Blizard Institute where I had the opportunity to investigate the effect of a novel protein on HIV capsid stability using microscopy. This work has contributed towards a publication in Methods. Our paper presented how advances in nanoscale imaging tools show the ability to study small structures such as HIV in their physiological context making a significant impact on biomedicine. Not only has this experience prompted me to develop my research skills, it has also shown me the extent to which experimental investigation requires patience and tolerance for ambiguity. However the rewarding experience reinforced my ambition to take part in more research and to take part in yet more publications. The 6 month research -project of this MSc will allow me to practice this ambition and explore the interplay between biological components examining the genetic and epigenetic phenomena of pathophysiological mechanisms. The focus of the department on complex metabolic disorders such as obesity and type II diabetes is of particular interest to me. Would relish the opportuniy to be part of a place that is laying the foundations for personalised medicine, leading to improved medical treatment for patients
and targeted lifestyle or pharmaceutical preventative strategies for high-risk

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