The effect of opium on diethylnitrosamine-induced gastrointestinal cancer in rats
Uncontrolled growth of abnormal cells and their spreading to another tissues ,these characterizing of cancers which mostly lead to death ,if their spreading is not controlled.Cancers are caused by chemical materials ,infectious organisms,tobacco and radiation as external factors and hormones,mutation and immune conditions as internal factors.(1)
Gastrointestinal cancers are the term for many cancers which affect the organs of digestive system. The cancer may affect the mouth ,esophagus ,stomach ,small and large intestine ;colon, rectum ,anus ,liver ,gallbladder and pancreas .In Iran , some researches report that cancers are the second cause of death ,following cardiovascular death.(2) Every year the percentage of digestive cancer reach to 38% of 51000 cases of cancers.(3) Cancer will overstep heart disease as the commonest cause of death. (4) There are many causes for GI cancer like; Chronic inflammation ( Chronic H. pylori infection and chronic viral hepatitis) , exposure to carcinogenic materials, genetic susceptibility, Smoking and dietary habits(alcohol , opium consumption, hot drinks, eating pickled vegetables, nutritional deficiencies(vitamin and mineral deficiencies), medications(non-steroidal anti-inflammatory drugs, …show more content…
Some epidemiological studies suggested that relationship between opium consumption and larynx cancer,(16) other researchers concluded that regular uses of opium can be accounted as risk factor for gastric adenocarcinoma. (17) Abnet CC et al concluded in their study that use of opium risk factor for esophageal cancer in Golstan in Iran ,(18) Also another study concluded the relationship between opium and esophageal cancer,(19) support that some researchers in their epidemiological study that link between opium ,tobacco and alcohol use and oesophageal squamous cell
Uncontrolled growth of abnormal cells and their spreading to another tissues ,these characterizing of cancers which mostly lead to death ,if their spreading is not controlled.Cancers are caused by chemical materials ,infectious organisms,tobacco and radiation as external factors and hormones,mutation and immune conditions as internal factors.(1)
Gastrointestinal cancers are the term for many cancers which affect the organs of digestive system. The cancer may affect the mouth ,esophagus ,stomach ,small and large intestine ;colon, rectum ,anus ,liver ,gallbladder and pancreas .In Iran , some researches report that cancers are the second cause of death ,following cardiovascular death.(2) Every year the percentage of digestive cancer reach to 38% of 51000 cases of cancers.(3) Cancer will overstep heart disease as the commonest cause of death. (4) There are many causes for GI cancer like; Chronic inflammation ( Chronic H. pylori infection and chronic viral hepatitis) , exposure to carcinogenic materials, genetic susceptibility, Smoking and dietary habits(alcohol , opium consumption, hot drinks, eating pickled vegetables, nutritional deficiencies(vitamin and mineral deficiencies), medications(non-steroidal anti-inflammatory drugs, …show more content…
Some epidemiological studies suggested that relationship between opium consumption and larynx cancer,(16) other researchers concluded that regular uses of opium can be accounted as risk factor for gastric adenocarcinoma. (17) Abnet CC et al concluded in their study that use of opium risk factor for esophageal cancer in Golstan in Iran ,(18) Also another study concluded the relationship between opium and esophageal cancer,(19) support that some researchers in their epidemiological study that link between opium ,tobacco and alcohol use and oesophageal squamous cell