Analysis Of Gamma-Glutamyl Transferase (GGT)

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Introduction
So what is GGT? GGT stands for Gamma-glutamyl Transferase, it is found on the cell surface that contribute to the extracellular catabolism of glutathione (GSH). The most GGT serum is derived from the liver, but it is also produced in many other tissues. GGT is primarily carried with lipoproteins and albumin in serum. The levels of GGT is determined by various factors such as alcohol intake, body fat content, plasma lipid/ lipoproteins and glucose levels, and also various medications (Whitfield, 2001, p.263-3553). As noted by Das, Nayak, and Vasudevan(2003, p.111-118) there are other biochemical markers that is also associated with alcohol such as Aspartate Aminotransferase (AST) activity, high-density lipoprotein cholesterol (HDL-C)
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Since it is large you can imagijne that it will have a lot of functions such as, it stores vital energy and nutrients, it manufactures proteins and also manufacvtures enzymes that is necessary for good health, it protects the body from diseases, it also breaks down or metabolizes and it removes harmful toxins, such as alcohol, from the body. Since the liver is the major organ for removeing toxins such as alcohol, a small amount ofalcohol can harm theliver if itisused with certain over-the-conter medication, like those that contain acetaminophen. This can all lead to the diagnosis of alcohol liver disease(ALD), and also hepatitis C which is often found in patients with ALD. There are three conditions which is included in ALD, fatty liver, alcoholic hepatitis,and also cirrhosis. Fatty liver being the first stage of ALD can be induced within a few weeks of heavy drinking. This disorder ismerked by a build-up of fat inside the liver cells, it can be reversed if drinking stops. If drinking continues for a longer period it can lead to more severe conditions like alcoholic hepatitis, which is inflammation in the liver, can also be fatal. If the drinking still continues this condition may lead to even more severe conditions like cirrhosis. In cirrhosis the healthy liver cells are replaced by fibrouis tissue, leaving the liver unable to perform the major functions. When the alcoholic hepatitis condition is reaached and the subject stops drinking, there might be a full recovery from liver disease orit might still progress to cirrhosis. Cirrhosis of the liver is a major cause of death in the United States (Yoon et al., 2002). There are treatment available, but the first step to recover is abstinence. Liver cirrhosis can also progress to liver cancer, which is the final fatal stage if not treated and if drinking doesn’t

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