Gallstone Disease Analysis

Improved Essays
The article that I found is about gallstone disease and how it is linked to diabetic patients. Gallstones are small hard deposits that are formed in the gallbladder. Gallstones can be cholesterol or mixed type. Most people have gallstones and do not even realize it. Gallstones are not soluble and must remain suspended in fluid and be transported into bile salts called micelles. If a person retains too much cholesterol, then the bile fluid turns into sludge; which thickens the fluid and contains the cholesterol and calcium bilirubinate. Cholesterol crystals will form if the condition gets worse and will eventually form gallstones. Some other reasons why gallstones form is due to the gallbladder not being able to empty normally, the cells lining …show more content…
Laparoscopic cholecystectomy is often used to surgically remove gallbladders and affects about 10% to 15% of the population in the United States; which is roughly about 25 million people. (Liu, 2012) There has been increasing reports in Taiwan from 4.3% to 10.75 that have increased with age and patients ranging from 20 to 39 years old have been reported of having GSD. The study of GSD have been an upward trend in the admission rates for treatment of gallstones since the 1990s and have been varied due to the study design, patient ethnicity, and geographic region. Some factors for these studies include old age, gender, genetics, diet, obesity, diabetes, and the use of oral contraceptives; which have been linked to the increase risk of GSD. (Liu, …show more content…
This design is a type of observational study and is used where one or more samples are selected to represent a population and are studied over time. This design is to collect information about the outcome of the interest and any exposure risk factors that may involve. This study is used for people who are disease-free of the study and data is collected from the outcome of the exposure to the risk factors. Cohort studies can be fixed or dynamic. A strength key in using this design would be that it is easy and cheap to use, the subjects can be matched; which reduces any influence of confounding variables, and standardization of outcome is possible. A weakness would be that the outcome of the interest would take time to happen, no randomization, blinding is difficult, or it’s difficult to identify due to confounding variables.
One ethical issue that could apply to this research would be informed consent. Informed consent is used to help ensure that any research participant can make a free choice on the study and allow the researchers legal authorization to conduct the study. By having informed consent, the participant has the right to know any procedures, risks, benefits, and the right to withdraw from research anytime and feel safe during the

Related Documents

  • Decent Essays

    Stanely Milgram was a social phycologist who conducted an experiment in 1963 about nonviolent people being capable of hurting others due to obeying the authority under pressure despite their feeling of remorse. The way the experiment received progression was by having people play the role of a teacher and a learner. The teacher obeys the authority and the learner had to memorize a certain amount of words. If the learner failed to the duty, he would received a punishment of a dose of high voltage shock. Although the purpose of the experiment was to test how the learner was capable of learning, it to was to test the capability of the teacher to continue the experiment whether or not they felt guilt.…

    • 456 Words
    • 2 Pages
    Decent Essays
  • Improved Essays

    Lastly, there must be an ethical selection of subjects. The Belmont Report states, “they should not offer potentially beneficial research only to some patients who are in their favor or select only "undesirable" persons for risky research” (The Belmont Report). Researchers must be far when selection their research…

    • 741 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Institutional Review Boards (IRB) are set in place to help regulate anthropological research as a way to protect the cultures and lives of the people that are the subjects. The intentions of these boards are set in place for a great reason. The issue lies in how the IRB’s have the ability to inhibit in depth research or even renders research already completed to be completely useless if it is deemed unethical or unauthorized. Institutional Review Boards often impede on the freedom of anthropologists that would otherwise make important discoveries. Because of this, I think that researches should be allowed a wider range of freedom than they currently are.…

    • 598 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Longitudinal Missing Data

    • 382 Words
    • 2 Pages

    Longitudinal cohorts have been widely used in epidemiological studies. These cohorts have been vital for the discovery of important risk factors associated with various diseases and public health issues in the last few decades (refs). Long term follow up of these cohorts will continue to provide valuable data that will lead to the discovery of novel risk factors associated with disease. One of the most important issue with longitudinal studies is the missing data at each follow up time (refs).…

    • 382 Words
    • 2 Pages
    Improved Essays
  • Improved Essays

    Gallstones Research Paper

    • 568 Words
    • 3 Pages

    Gallstones are formed when a chemical imbalance in the bile chemical makeup occurs and roughly effects about 10-15% of all Western adults.4 In the human body, the gallbladder produces bile which is made up of components of not only bile salts and phospholipids but also cholesterol. When the liver secretes an excessive amount of cholesterol or an increase consumption of salt and water, build up of cholesterol occurs in the gallbladder forming a gallstone. Often, gallstones are small enough to pass without complications but larger stones create blockages and problems. When a stone is large enough it can become lodged in the opening of the gallbladder and causes painful contractions of smooth muscle.…

    • 568 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    Common bile duct stones are concomitant with gallstones in 10-15% of the patients, with the percentage of association between 8% and 15% in patients under the age of 60 and between 15% and 60% in patients over the age of 601. A standard treatment for concomitant common bile duct (CBD) and gallstones remains controversial and there is no consensus on the optimal management strategy, which could be due to multiple factors, including the level of suspicion for choledocholithiasis, preferences (patient and physician), resources, and the expertise of the surgeons, endoscopists, and radiologists2. The well-known and popular treatment options include: (1) laparoscopic cholecystectomy after endoscopic treatment (a two-steps procedure), (2) endoscopic treatment…

    • 587 Words
    • 3 Pages
    Improved Essays
  • Decent Essays

    Gall Bladder Stones

    • 367 Words
    • 2 Pages

    Gallstones or Gall Bladder stones are hard deposits present in your gall balder which are mainly made up of cholesterol, salt, or bilirubin, that are discarded red blood cells. These stones move stealthily inside the gall bladders. The gall bladder is a small organ that functions as the storage place for bile (a digestive fluid) that is made in the liver. These stones also vary in size as in some cases, they are as small as grains or sometimes they are large as the size of a plum.…

    • 367 Words
    • 2 Pages
    Decent Essays
  • Decent Essays

    Hyperlipidemia Hyperlipidemia is when your body has too much fat in the blood. This condition can be helped by eating more foods that are high in fiber. Doctors suggests that you should eat about ten percent more fiber than you would normally eat. Type 2 diabetes Type 2 diabetes is also known as hyperglycemia. This is the rise of high sugar levels in the blood.…

    • 135 Words
    • 1 Pages
    Decent Essays
  • Superior Essays

    Research Problem Inadvertent Hypothermia is a prevalent disease that has been observed to bring about adverse effects. It is a condition in which the body lacks the ability to maintain the optimal temperatures required of the body. It has harmful impacts on the health of individuals that leads to the patients incurring a lot of costs in terms of medical care associated with it. Many of its effects include impaired immune function, cardiac complications, thermal discomfort, and increased incidence of wound infections among others (Hegarty et al., 2009).…

    • 1096 Words
    • 5 Pages
    Superior Essays
  • Improved Essays

    What Is Gallstones?

    • 227 Words
    • 1 Pages

    Gallstones Introduction Gallstones are solid materials that are formed from the digestive fluids made by the liver. Symptoms Many people may have gallstones and does not show symptoms. They might not even know they have gallstones. Often, a gallstone may leave the gallbladder and goes into the passageway from the gallbladder to the intestine.…

    • 227 Words
    • 1 Pages
    Improved Essays
  • Improved Essays

    Cholelithiasis is the most common disorder of the biliary tract and is the one of the most common diseases affecting emergency-room patients with epigastric pain, nausea, vomiting, abdominal pain, and loss of appetite (Jessri & Rashidkhani, 2015). A key factor in the susceptibility of cholelithiasis is genetics. Individuals are five times more likely to develop cholelithiasis when a family member has been diagnosed with the disorder (Stinton & Shaffer, 2012). The prevalence of cholelithiasis increases with age and is higher in woman than in men (Gustavsson et al., 2011). The female to male ratio is 4:1 in younger subjects and decreases to 2:1 in older age groups.…

    • 545 Words
    • 3 Pages
    Improved Essays
  • Great Essays

    Although statistical data and research shows there are healthcare disparities as it relates to minorities, much isn’t done to change negative patterns. However, researchers’ have chosen to examine the healthcare racial inequalities of African Americans. Cultural differences, and racial conscious and unconscious are factors that contribute to the gap in African American health. Therefore, collecting only medical data and physician behaviors towards certain diagnosis, is not enough to determine or conclude that there aren’t any deep rooted unforeseen components that play into racialist thinking by physicians.…

    • 2046 Words
    • 9 Pages
    Great Essays
  • Improved Essays

    Ethical Concerns Experimental design is a field whereby ethical concerns are almost always a top priority. Although most individuals see ethical norms as common sense, they often vary from culture to culture and there can be discrepancies in the interpretation even by members within a certain cultural group. Furthermore, it is vital to determine any potential ethical concerns contained within an experiment and address those concerns in order to reduce their potential impact on the results. The first potential ethical concern that may be encountered during our experiment is an experimenter either intentionally or accidentally falsifying, fabricating or misrepresenting the data that is collected from the test subjects.…

    • 713 Words
    • 3 Pages
    Improved Essays
  • Improved Essays

    The code of ethics goes back since the Hippocratic code 2.500 years ago. The aim of the code is to provide ethical standards and to guide the psychologists to make ethical decisions. The first American psychological association (APA), ethics code was published in 1953, and was adopted by other countries. The British psychological society (BPS) published its first code of ethics in 1983. Later on, globalization created the need for international ethical standards and shared principles (Allan & Love, 2010).…

    • 1720 Words
    • 7 Pages
    Improved Essays
  • Improved Essays

    Ethical guidelines are crucial in research to minimise unnecessary physical or psychological harm to participants in an experiment. Before ethical guidelines existed in research, several experiments were not conducted ethically. In 1963, American psychologist Stanley Milgram conducted Milgram’s Study of Obedience investigating participants' obedience towards authority. The study demonstrated multiple ethical issues which proved the importance of ethics in research. This report will address the ethical principles that Milgram's study covered poorly and how they could be modified to improve the study.…

    • 1040 Words
    • 5 Pages
    Improved Essays