Farber lipogranulomatosis, or simply Farber’s disease, is a lysosomal storage disorder that involves the hydrolysis and use of lipids. A lysosomal storage disorder is a defect in the function of a lysosome, enzymes that hydrolyze large molecules and then move the fragments on to other parts of the cell for other uses. Farber’s disease is a rare, genetic condition that involves a deficiency in the enzyme, ceramidase. Ceramidase is a lysosomal acid that causes cell growth, cellular differentiation, cell adhesion, the movement of cells and the death of cells. The body is unable to produce ceramidase with Farber’s disease, thus causing the buildup of ceramide.
A gene is a section of DNA that codes for one protein. When there is a mistake in the
A gene is a section of DNA that codes for one protein. When there is a mistake in the