Evidence Based Study Examples

An example of the limitation is deep brain stimulation for patients with Parkinson’s resulting a lack of controlled data, mismatch evidence, insufficient medication effect in the clinical practice. Another instance of the limitation in the EBM are the patients with non-motor symptoms of PD. Some areas such as constipation, anxiety, fatigue, insomnia, sexual dysfunction urinary incontinence have not been thoroughly discussed in the research for symptoms of PD patients which can be considered as an evidence gap for standard of care therapy. Pharmacologic treatments such as amantadine, dopamine agonist, anticholinergics, levodopa formulations have lacking evidence with regards to their effectiveness for the delay progression or preventing the progress of PD. Furthermore, some medications serve as a symptomatic monotherapy such as amantadine and anticholinergics are considered as probable or likely effective, dopamine agonist like cabergoline and ropinrole are updated to be effective as a symptomatic …show more content…
The criteria used for these reviews includes research studies including randomized controlled studies were from Consolidated Standards of Reporting Trials (CONSORT) recommendations.
Almost 89% of PD patients during the progression of the disease have speech and voice impairment including laryngeal disorder and problems with articulation of words. Studies have shown that only 3-4% of PD patients’ receive speech therapy. The reviews concluded that speech therapy not necessarily needed in the prevention or progression in patients with PD and preventing complication of motor symptoms. The researchers concluded there were insufficient proof or valuable evidence that the benefit of language and speech therapy are needed for speech impairment in PD patients (Ramig, Fox, & Sapir, 2008).
Parkinson’s Medication by