Chapter 1 THE PROBLEM AND ITS SCOPE
Introduction
Hyperlipidemia is not new to Filipinos. Hyperlipidemia is the abnormal elevation of any lipids like cholesterol and triglycerides in the blood (Saunders, 2007). According to the 2008 National Nutrition Survey (NSS) conducted by Food and Nutrition Research Institute of the Department of Science and Technology (FNRI-DOST) the total cholesterol level among Filipino adults increases to 10.2 (mg/dL) from the 2003 survey result 8.5 (mg/dL). Hyperlipidemia is mostly caused by sedimentary lifestyle like smoking, obesity and not exercising. Treatable medical conditions caused hyperlipidemia includes kidney disease, an underactive thyroid gland, diabetes and even pregnancy. Hyperlipidemia can also be inherited if other family members have the disease (Society of Vascular Surgery, 2010). There are various preparations available in the market intended for treatment of this disease. But it seems to be innate for Filipinos especially in rural areas to use alternative medicines because it is safer and cheaper. Though these alternative medicines were already in use for years, their claims are yet to be validated. Alternative medicines include Eucheuma cottonii a seaweeds that is used in the production of carrageenan, an important product used in food processing, industrial use and cosmetics, as well as a source of food and living in Indonesia and the Philippines (Neish IC et al., 2003). Polyphenols are constituents found in Eucheuma cottonii that act as antioxidants (Shamsabadi FT et. al, 2013). Polyphenols protect the cells and other body chemicals against damage caused by free radicals a reactive atom that causes damage to the tissue in the body. The presence of polyphenol in Guso could be the cause of its hypolipidemic activity and this study is conducted to assess this claim. Since Guso is an alternative medicine, this could help solve the problems that arise in the use of modern medicine which includes the high cost of conventional drugs, their unavailability in rural areas and the relatively high …show more content…
Pharmacists.The result of the study will give pharmacist additional information regarding the possible benefits of using Eucheuma cottonii on patients with hyperlipidemias. Community.The study may help the community consider Eucheuma cottonii as part of their diet regimen. Liceo de Cagayan University.This study will contribute to the research program of the university. Students.The study will give the students new knowledge about the uses of Eucheuma cottonii. Researchers.The result of the study will provide information to be used by future researchers who are interested in furthering the studies regarding antihyperlipidemic effect of Eucheuma …show more content…
Limitations of the study include the limited expertise of the researchers, any unexpected death, escape, failure to environmental adaptation, and sudden illness of the rabbit. It is also limited to the materials and equipment available in Cagayan de Oro City
DEFINITION OF TERMS Eucheuma cottonii (Guso). This refers to the plant that is being studied. Hyperlipidemias. This refers to the rabbit used in the study that have high levels of cholesterol. Hypolipidemic. This term refers to the ability of the extract to lower the cholesterol levels of the test animals. Alternative medicine. This term refers to Eucheuma cottonii (Guso). Confirmatory Test. This refers to the methods used to test the presence of polyphenol in the Eucheuma cottonii extracts. Plant extract. This refers to the crude mixtures extracted from Eucheuma cottonii (Guso) . Polyphenol. This refers to the active constituent of Eucheuma cottonii that is being tested for its hypolipidemic
Introduction
Hyperlipidemia is not new to Filipinos. Hyperlipidemia is the abnormal elevation of any lipids like cholesterol and triglycerides in the blood (Saunders, 2007). According to the 2008 National Nutrition Survey (NSS) conducted by Food and Nutrition Research Institute of the Department of Science and Technology (FNRI-DOST) the total cholesterol level among Filipino adults increases to 10.2 (mg/dL) from the 2003 survey result 8.5 (mg/dL). Hyperlipidemia is mostly caused by sedimentary lifestyle like smoking, obesity and not exercising. Treatable medical conditions caused hyperlipidemia includes kidney disease, an underactive thyroid gland, diabetes and even pregnancy. Hyperlipidemia can also be inherited if other family members have the disease (Society of Vascular Surgery, 2010). There are various preparations available in the market intended for treatment of this disease. But it seems to be innate for Filipinos especially in rural areas to use alternative medicines because it is safer and cheaper. Though these alternative medicines were already in use for years, their claims are yet to be validated. Alternative medicines include Eucheuma cottonii a seaweeds that is used in the production of carrageenan, an important product used in food processing, industrial use and cosmetics, as well as a source of food and living in Indonesia and the Philippines (Neish IC et al., 2003). Polyphenols are constituents found in Eucheuma cottonii that act as antioxidants (Shamsabadi FT et. al, 2013). Polyphenols protect the cells and other body chemicals against damage caused by free radicals a reactive atom that causes damage to the tissue in the body. The presence of polyphenol in Guso could be the cause of its hypolipidemic activity and this study is conducted to assess this claim. Since Guso is an alternative medicine, this could help solve the problems that arise in the use of modern medicine which includes the high cost of conventional drugs, their unavailability in rural areas and the relatively high …show more content…
Pharmacists.The result of the study will give pharmacist additional information regarding the possible benefits of using Eucheuma cottonii on patients with hyperlipidemias. Community.The study may help the community consider Eucheuma cottonii as part of their diet regimen. Liceo de Cagayan University.This study will contribute to the research program of the university. Students.The study will give the students new knowledge about the uses of Eucheuma cottonii. Researchers.The result of the study will provide information to be used by future researchers who are interested in furthering the studies regarding antihyperlipidemic effect of Eucheuma …show more content…
Limitations of the study include the limited expertise of the researchers, any unexpected death, escape, failure to environmental adaptation, and sudden illness of the rabbit. It is also limited to the materials and equipment available in Cagayan de Oro City
DEFINITION OF TERMS Eucheuma cottonii (Guso). This refers to the plant that is being studied. Hyperlipidemias. This refers to the rabbit used in the study that have high levels of cholesterol. Hypolipidemic. This term refers to the ability of the extract to lower the cholesterol levels of the test animals. Alternative medicine. This term refers to Eucheuma cottonii (Guso). Confirmatory Test. This refers to the methods used to test the presence of polyphenol in the Eucheuma cottonii extracts. Plant extract. This refers to the crude mixtures extracted from Eucheuma cottonii (Guso) . Polyphenol. This refers to the active constituent of Eucheuma cottonii that is being tested for its hypolipidemic