Ethical dilemmas commonly faced in the nursing profession arises when nurses are at crossroads with moral ideologies and competing demands of miscellaneous parties—that is, the client’s desires, the physician’s orders, the family’s demands, bureaucracy of the hospital, the law, and the nurse’s physical and emotional limitations (Chambliss, 1996, p. 93). One common ethical issue encountered in clinical settings is the interjection of advance directives to the nurse’s innate duty to care. Specifically, this paper presents a case vignette about a Jehovah’s Witness refusing a necessary life-saving blood transfusion citing religious principles. After analysing the ethical dilemma, I strongly believe that the client’s autonomical decision to refuse the blood transfusion takes precedence over the nurse’s duty to care; this is further supported using ethical theories (consequentialism and deontology), biomedical principles (beneficence, non-maleficence, autonomy, veracity, and fidelity), and the Canadian judicial laws.…