Essay On The Effect Of Cocaine On Glucose Metabolism

Improved Essays
Introduction
Many people are aware that drugs such as cocaine are known to have a large effect on one’s body. Drug abusers lose a tremendous amount of weight, indicating an increase in metabolism. In the scientific article “Metabolic Mapping of the Effects of Cocaine during the Initial Phases of Self-Administration in the Nonhuman Primate”, Porrino, Lyons, Miller, Smith, Friedman, Daunias, and Nader trained rhesus monkey to self administer a certain dosage of cocaine and observed the effects of the drug on glucose metabolism. Interestingly, they found that glucose metabolism both increased and decreased according to certain areas of the brain.
Since cocaine is seen to have some sort of effect on monkeys, what effect will other drugs have on the metabolism of other animals? In this lab, the metabolic rates of Carassius auratus, commonly know as goldfish, will be measured and compared to by looking at oxygen consumption,
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Because the p-value of the pooled data is 0.868 and greater than 0.05, there is a failure to reject the null hypothesis and therefore it is appropriate to accept the statement that the metabolic rates of goldfish in fish water (control) and nicotine infused fish water (experiment) are the same. In other words, nicotine does not have a significant effect on metabolism. The results for the individual labs were interesting. When comparing Figure 1 and 2, there is a decrease in oxygen concentration and therefore an increase in metabolic rate. However, when looking at Figure 3 and 5 the slope changes from -0.0005 to -9E-05, implying a decrease in metabolic rates. This discrepancy may have been caused by different factors throughout the lab. The biggest concern with the validity of this lab would involve the dilution of the nicotine infused water in the second trial. Although the dilution may have skewed the data, it was a necessary step to ensure the safety of the

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