Inflammation is the body’s response to muscle and bone injury and a local reaction to damaged cells in the body. The organisation of the repair process will occur due to macrophage phagocytosis of dead cells, proliferation of blood cells and fibroblasts at the edge of the damaged area, fibroblasts migrating to the injury site forming a slight framework of connective tissues, fibroblast producing collagen – thus providing strength, a new capillary network being established at the injury site and collagen fibres forming scar tissue. During the acute onset the dilatation of capillaries allow fluid to seep out into the surrounding tissues, this reaction causes redness and heat. The excess fluid causes an increase in pressure which subsequently leads to tenderness and swelling. Damaged nerve endings where applicable present pain and the plasma protein fibrinogen is released to help the blood clot, leukocytes ingest and remove bacteria, also known as phagocytosis. As healing is in most parts immediate, the body responds in a variety of ways, especially inflammation which is the immediate response to trauma, pain, erythema and heat. Inflammation is the first response to repair muscle and bone injuries
Inflammation is the body’s response to muscle and bone injury and a local reaction to damaged cells in the body. The organisation of the repair process will occur due to macrophage phagocytosis of dead cells, proliferation of blood cells and fibroblasts at the edge of the damaged area, fibroblasts migrating to the injury site forming a slight framework of connective tissues, fibroblast producing collagen – thus providing strength, a new capillary network being established at the injury site and collagen fibres forming scar tissue. During the acute onset the dilatation of capillaries allow fluid to seep out into the surrounding tissues, this reaction causes redness and heat. The excess fluid causes an increase in pressure which subsequently leads to tenderness and swelling. Damaged nerve endings where applicable present pain and the plasma protein fibrinogen is released to help the blood clot, leukocytes ingest and remove bacteria, also known as phagocytosis. As healing is in most parts immediate, the body responds in a variety of ways, especially inflammation which is the immediate response to trauma, pain, erythema and heat. Inflammation is the first response to repair muscle and bone injuries