Conclusion
In review of the broad spectrum of studies, it proves that metformin is a better drug choice for treating pregnant women who have GDM. The use of metformin promotes glycemic control (Ibrahim, M, 2014). These studies produced marginal biases, and the methods used to conduct the research were suitable. The data gathered from each study indicated that metformin is similar to insulin in glycemic control. By using metformin, the body reduces the amount of glucose production, it also helps promote insulin sensitivity and increases glucose uptake. Use of metformin in gestational diabetes was associated with fewer adverse outcomes compared with insulin. Women treated with insulin had higher rates of C-section than women treated with metformin or diet. Metformin is not associated with increased perinatal complications. There is no maternal or fetal risks with the use of metformin. …show more content…
It reduces occurrence of neonatal respiratory distress syndrome, hypoglycemia, and NICU admission. Children exposed to metformin will develop less visceral fat and be more insulin sensitive. The use of metformin during pregnancy assisted in prevention of fetal macrosomy. As a result, the mean birth weight in infants were higher with the use of insulin than that with metformin. The prevalence of large gestational age was higher 10.0% in insulin group than compared to the metformin groups of 8.5%. (Ijas, H, 2010). However, the follow up on children from gestational diabetic mothers showed that there was no real significant adverse effect of prenatal metformin exposure on motor, linguistic, to social development during the first 18 months compared with
In review of the broad spectrum of studies, it proves that metformin is a better drug choice for treating pregnant women who have GDM. The use of metformin promotes glycemic control (Ibrahim, M, 2014). These studies produced marginal biases, and the methods used to conduct the research were suitable. The data gathered from each study indicated that metformin is similar to insulin in glycemic control. By using metformin, the body reduces the amount of glucose production, it also helps promote insulin sensitivity and increases glucose uptake. Use of metformin in gestational diabetes was associated with fewer adverse outcomes compared with insulin. Women treated with insulin had higher rates of C-section than women treated with metformin or diet. Metformin is not associated with increased perinatal complications. There is no maternal or fetal risks with the use of metformin. …show more content…
It reduces occurrence of neonatal respiratory distress syndrome, hypoglycemia, and NICU admission. Children exposed to metformin will develop less visceral fat and be more insulin sensitive. The use of metformin during pregnancy assisted in prevention of fetal macrosomy. As a result, the mean birth weight in infants were higher with the use of insulin than that with metformin. The prevalence of large gestational age was higher 10.0% in insulin group than compared to the metformin groups of 8.5%. (Ijas, H, 2010). However, the follow up on children from gestational diabetic mothers showed that there was no real significant adverse effect of prenatal metformin exposure on motor, linguistic, to social development during the first 18 months compared with