Essay Of Ondansetron

In adult patients undergoing general anesthesia, does ondansetron decrease postoperative nausea and vomiting (PONV) compared to general anesthesia without antiemetics? The purpose of this study is to determine the effect of ondansetron, in preventing and treating postoperative nausea and vomiting, under different conditions of general anesthesia. The scope of this study covers the effects of ondansetron administered in combination with general anesthetics and the patient’s response in postoperative care. A preliminary, randomized, control study was conducted on two hundred and forty patients allocated into six groups: Group I, anesthesia was maintained with sevoflurane; Group II, anesthesia was maintained with sevoflurane and 8 mg of ondansetron; Group III, anesthesia was maintained with propofol; Group IV, anesthesia was maintained with propofol and 8 mg of ondansetron; Group V, anesthesia was maintained with sevoflurane and propofol; Group VI, anesthesia was maintained with sevoflurane combined with propofol and 8 mg of ondansetron (Zhang, Shen, You, Zhu, and Tang, 2013). It was determined that group II, IV, and VI had a lower incidence of postoperative nausea and vomiting compared to group I, …show more content…
Zhang, Shen, You, Zhu, and Tang (2013) used a preliminary, randomized, control study to experiment and collect data. Data was collected using direct questioning by one anesthesiologist, who was unaware of the medications that were administered to the patient. All episodes of PONV were recorded and evaluated within 24 hours of the surgical procedure, documenting results from 5 different postoperative time frames (0–4 h, 4–8 h, 8–12 h, 12–16 h, and 16–24 h). The research was based on the effects of ondansetron administered in combination with general anesthetics and the patient’s response in postoperative