Epidemiology Of Sepsis Essay

Epidemiology of sepsis: Sepsis represents a clinical syndrome in which both body’s immune and coagulation systems react to an infection1.It remains an ongoing challenge and one of the commonest causes of morbidity and mortality worldwide2. Although we have improved our understanding of its pathophysiology, it causes most of the hospitalizations and admissions to ICU3. Sepsis is fatal and costly, it is considered the 10th leading cause of death in the US4, and WHO also reported that more than 1 million in the US are affected with sepsis and half of them lose their lives5. Every year in the US, sepsis accounts for over 750,000 hospitalizations, 215,000 deaths and $16.7 billion in health care expenses6. Furthermore, sepsis is …show more content…
Additionally, the more recent research found that sepsis contributes to between one third to one-half of mortalities in the US hospitals, most of them reached hospitals with sepsis and didn’t acquire it in the hospital13. There is a notable paucity in the data that describes the global epidemiology of sepsis14, one of the reasons is the problem that sepsis is rarely mentioned in the statistics of the global burden of disease15, the most recent report attributed death to the original infection that caused sepsis with ignorance of the fact that infections result from sepsis cause many deaths, not the infection itself15. However, Short-term and long-term morbidity and mortality associated with sepsis is still a major public health concern16. Surprisingly, population-level epidemiological records of sepsis have still not yet been comprehensively studied17.All the available records come from high-income countries which is a problem as high-income countries represent only 13% of the world