Drug induced hepersensitivity syndrome (DIHS) is characterized by fever, rash and an involvement of the internal organs, mainly the liver, myocardium, kidneys or lungs, which may develop within 1–8 weeks after exposure to the offending drug. The diagnosis of DIHS is based on the characteristic manifestations triggered by the drug and may be supported by eosinophilia, elevated markers of inflammation and abnormal organ function tests, such as liver function tests[8]. Hypereosinophilic syndromes (HES) are a set of relatively rare, heterogeneous disorders characterized by persistent eosinophilia and organ involvement/dysfunction in which other clinical entities have been excluded[9]. Eosinophilic hepatitis develops in response to some medications and to helminth parasites. We present a case report of a patient with drug induced hypersensitivity with subsequent eosinophilia with pancreatitis, hepatitis and gastritis. We will also discuss conditions with eosinophilia and review the
Drug induced hepersensitivity syndrome (DIHS) is characterized by fever, rash and an involvement of the internal organs, mainly the liver, myocardium, kidneys or lungs, which may develop within 1–8 weeks after exposure to the offending drug. The diagnosis of DIHS is based on the characteristic manifestations triggered by the drug and may be supported by eosinophilia, elevated markers of inflammation and abnormal organ function tests, such as liver function tests[8]. Hypereosinophilic syndromes (HES) are a set of relatively rare, heterogeneous disorders characterized by persistent eosinophilia and organ involvement/dysfunction in which other clinical entities have been excluded[9]. Eosinophilic hepatitis develops in response to some medications and to helminth parasites. We present a case report of a patient with drug induced hypersensitivity with subsequent eosinophilia with pancreatitis, hepatitis and gastritis. We will also discuss conditions with eosinophilia and review the