Ebp Research Paper

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EBP Project Development: Conclusion from the article # 1 Although the research article “Opioids, Substance Abuse & Addictions Section: Changes in Prevalence of Prescription Opioid Abuse after Introduction of an Abuse-Deterrent Opioid Formulation.” did not specifically pertain to the nursing practice. Never the less, the results of this observational, a cross-sectional study revealed very important data pertaining abuse-deterrent formulations (ADF) of opioids, including control-release (CR) opioids, extended-release (ER) opioids, and immediate release (IR) formulations of opioids and prevalence of prescription opioids abuse. The findings of this research suggest a change in the prevalence and pattern of abuse for these specific products. The increase in abuse of all prescription opioids in the post-ADF period was observed, and especially a significantly greater abuse of ER opioids in the post-ADF period. The abuse nearly threefold, relative risk RR=2.91, 95% confidence interval CI=2.59-3.27, and probability level P˂0.0001 respectively. The results of this …show more content…
The results of the study were staggering. At 18th month after initial treatment Half (48.4%) reported prescription opioid use during past month. Also, treatment response to brief bup-nx treatment was overwhelmingly poor, only 7% had successful opioid use outcome. The opioid agonist treatment and participation in extended treatment phase had the best outcome 16.7% success rate. Of particular interest is that in this population, the multivariable analysis in this study showed that greater pain severity at baseline was directly linked to opioid dependence at 18

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