The cancer cells under stress use EMT phenomenon as cell survival mechanism to escape apoptosis, anoikis and general immune response. Autophagy triggered in response to stress conditions like starvation, is also used by cancerous cells for survival by recycling of cellular components. There is a cross talk between pathways involved in EMT and autophagy. The involvement of TGF-β signalling pathway had been observed induction of EMT and autophagy in many cell types. Autophagy is a context dependent phenomenon. It can act as oncosuppressor by removing defected cellular components during early stages of cancer. However in established cancers, it helps cancer cells by providing essential nutrients for metabolism. mTOR inhibits autophagy and promotes
