Dry eye is defined as a “multifactorial disease of the tears and ocular surface that results in symptoms of a lack of comfort, visual troubles, and tear film instability with possibility damage to the ocular surface.(1)The Risk factors for dry eye disease are High level of evidence is about Age, Female sex, Postmenopausal estrogen therapy, Antihistamines, Collagen vascular disease, Corneal refractive surgery, Irradiation, Hematopoietic stem call transplantation, Vitamin A deficiency, Hepatitis C and, Androgen insufficiency, Moderate level of evidence is about Medications such as tricyclic antidepressants, selective serotonin reuptake inhibitors, diuretics, beta-blockers, Diabetes mellitus, HIV/HTLV1 infection, Systemic chemotherapy, Cataract
