There are four ways of administering a drug which are as follows:
Oral: This is the simplest way to consume a drug. But it is the slowest method of producing the desired effect, since the drug has to pass through more body organs before reaching the brain. Figure i: ORAL DRUG CONSUMPTION
Injection: The fastest way of producing the desired effect is through directly injecting the drug into the bloodstream.
Inhalation: The drug inhalation causes its movement across the air sacs in the lungs before entering the blood stream. Figure ii: DRUG CONSUMPUTION THROUGH SMOKING
Direct absorption: The nasal membrane absorbs cocaine when it is sniffed. This can be considered as one example of this type. Smokeless tobacco could be another example.
There are 2 major spheres that need to be taken into consideration while designing a drug:
1. Drug target 2.Drug metabolism
DRUG PROCESSING
There are four stages in the physiological handling of a drug:
Absorption: Drug absorption is the process by which drugs move into the blood stream after administration. Absorption affects the bioavailability of a drug. Factors that affect absorption include:
The way a drug product is designed and manufactured.
Its physical and chemical properties.
The …show more content…
After absorption, the drug circulation takes place throughout the body with the help of the recycled blood from the heart in about a minute. The largest part of this blood reaches the brain. This means that all drugs are carried to the brain, but not all can enter it as there is a blood-brain barrier surrounding the brain to prevent impurities from entering it. Once drug molecules make it across this barrier, they move to receptor sites throughout the body. Once absorbed, the drug molecules differ in