Hudspeth has not patented his discovery since it is scientific knowledge that will be used to promote the field and not so much as a product. It is unlcear whether anyone else was attempting to patent those discoveries. His recent discovery of Sox4 and Sox11 activation of downstream genes provides new insight into the function and development of hair cells. However, this information just scratches the surface because the pathway could be enormously complicated with dozens of possible components that are interacting in some manner. Whether that be activating or repressing other downstream genes is currently unknown. The major questions that are being brought up from this discovery are: What are the downstream targets of Sox4 and Sox11? What genes do they activate or repress and what do those genes do? Are there any other layers of transcription factors? What are the signaling proteins such as second messengers? And where does the progression end? The overall goal is to find a method to overcome deafness. The hope is that if there is a blueprint provided of how these cells differentiate and by what means, then we would be able to control those portions and turn them on or off in order to help restore the hearing of individuals. This would cause the persuading of the system to produce more hair cells. This could lead to the possibility of not having patients undergo surgery for the cochlear implant, a sort of artificial ear that allows patients to hear if their hair cells are damaged and they are
Hudspeth has not patented his discovery since it is scientific knowledge that will be used to promote the field and not so much as a product. It is unlcear whether anyone else was attempting to patent those discoveries. His recent discovery of Sox4 and Sox11 activation of downstream genes provides new insight into the function and development of hair cells. However, this information just scratches the surface because the pathway could be enormously complicated with dozens of possible components that are interacting in some manner. Whether that be activating or repressing other downstream genes is currently unknown. The major questions that are being brought up from this discovery are: What are the downstream targets of Sox4 and Sox11? What genes do they activate or repress and what do those genes do? Are there any other layers of transcription factors? What are the signaling proteins such as second messengers? And where does the progression end? The overall goal is to find a method to overcome deafness. The hope is that if there is a blueprint provided of how these cells differentiate and by what means, then we would be able to control those portions and turn them on or off in order to help restore the hearing of individuals. This would cause the persuading of the system to produce more hair cells. This could lead to the possibility of not having patients undergo surgery for the cochlear implant, a sort of artificial ear that allows patients to hear if their hair cells are damaged and they are