Synopsis Paper- Dr. Cheatwood
During Dr. Cheatwood’s presentation he discussed the research methods that he uses for the biomedical research model. Firstly he discussed the impact and importance of stroke research. He notes that according the American Heart Association, there are 800,000 new stroke victims each year in the United States. There are two types of strokes: ischemic and hemorrhagic. One third of stroke victims are left with severe permanent deficits. Some risk factors that Dr. Cheatwood mentions include genetics, gender, and previous history of stroke. Moreover, Dr. Cheatwood states that recovery from stroke associated with neuroanatomical plasticity. Some of the approaches for stroke research include looking at reducing stroke damage, enhancing recovery and plasticity, therapeutic compounds and physical therapy. …show more content…
According to Dr. Cheatwood, a biomedical model is a way to study human disease without using humans. Due to ethical concerns, models are necessary when studying human disease. Model types can be in vivo or in vitro. In vitro models are models which look at cell culture. The easier way to look at in vitro models is by using the immortalized cell line. This can be a cancer cell or other cell which has been infused with a cancer cell while it continues to divide. Immortalized cell lines are beneficial because they reduce the need to obtain new cells since the cells continue to divide. Slice cultures is another example of a method used during in vitro research models. Slice cultures take a part of tissue or organ and preserve it to make approximates. Through in vitro research, protein expression, MRNA expression, and cell survival can be studied. One fundamental weakness that the in vitro models presents is that it cannot replicate the same conditions in a human
During Dr. Cheatwood’s presentation he discussed the research methods that he uses for the biomedical research model. Firstly he discussed the impact and importance of stroke research. He notes that according the American Heart Association, there are 800,000 new stroke victims each year in the United States. There are two types of strokes: ischemic and hemorrhagic. One third of stroke victims are left with severe permanent deficits. Some risk factors that Dr. Cheatwood mentions include genetics, gender, and previous history of stroke. Moreover, Dr. Cheatwood states that recovery from stroke associated with neuroanatomical plasticity. Some of the approaches for stroke research include looking at reducing stroke damage, enhancing recovery and plasticity, therapeutic compounds and physical therapy. …show more content…
According to Dr. Cheatwood, a biomedical model is a way to study human disease without using humans. Due to ethical concerns, models are necessary when studying human disease. Model types can be in vivo or in vitro. In vitro models are models which look at cell culture. The easier way to look at in vitro models is by using the immortalized cell line. This can be a cancer cell or other cell which has been infused with a cancer cell while it continues to divide. Immortalized cell lines are beneficial because they reduce the need to obtain new cells since the cells continue to divide. Slice cultures is another example of a method used during in vitro research models. Slice cultures take a part of tissue or organ and preserve it to make approximates. Through in vitro research, protein expression, MRNA expression, and cell survival can be studied. One fundamental weakness that the in vitro models presents is that it cannot replicate the same conditions in a human