Diastolic Dysfunction

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Diabetes is an important risk factor of cardiomyopathy which evolve to heart failure. A detailed evaluation of the cardiovascular function in diabetes mellitus by echocardiography is useful to demonstrate left ventricular diastolic dysfunction. The association of diabetes with hypertension, obesity and dyslipidemia derange the left ventricular diastolic function earlier. The study population comprised of 73 (60.8%) males and 47 (39.2%) females among the total of 120 patients with history of type 2 diabetes mellitus of any duration. The mean age of the subjects was 50.4±8.358 years. Diabetic patients with diastolic dysfunction was compared with the population with normal echocardiogram findings using several parameters such as age, gender, body …show more content…
This finding is in accordance with the study conducted by Patil et al in which the prevalence rate of diastolic dysfunction was 54.33% [1]. Diastolic dysfunction was found to be higher in the older people of more than 45 years of age compared to the individuals in the age group of less than 45 years. The prevalence of diastolic dysfunction in the males and females were 25 (20.8%) and 41 (34.2%) respectively. Higher prevalence rate of diastolic dysfunction was noted among the elderly diabetic women in the study by Alfried Germing et al [7]. This similar trend was also observed in the study under discussion. Among the 66 diabetic patients with diastolic dysfunction, obesity was observed in 42 individuals with a body mass index of more than 23 kg/m2. This result was supported by the study by Russo et al [8] which showed a strong correlation between obesity and left ventricular diastolic dysfunction. Diastolic dysfunction was more prevalent in the patients with higher …show more content…
The results from this study reinforces the vital role of echocardiogram to evaluate the diastolic functional parameters. Early diagnosis and therapeutic interventions in diabetes mellitus before the deleterious cardiac sequelae become established, modulate the cardiac metabolism and prevent congestive cardiac failure.
Acknowledgement: The author would like to thank the Head of the Department, Professors, Associate Professors, Assistant Professors and non-teaching staff of Departments of General Medicine and Cardiology, Tagore Medical College and Hospital, for guiding me for each & every step of this research work by

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