Introduction Brain imaging techniques have been a prominent resource in developing research associated with several cognitive disorders including: Alzheimer’s disease, concussions, MCI, etc. Researchers have been developing novel approaches to help develop solutions and/or gain better insight for what disease, injuries, and impairment have on the brain. One of the more recent techniques that has been developed is fMRI. One of the cognitive issues it can look at is mild cognitive impairment, which is a stage of impairment before Alzheimer’s disease. The purpose of this paper is to look at mild cognitive impairment and what it looks like in neurological imaging to determine whether they can be used for diagnosing MCI and create better treatments.
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It usually involves problem with memory, language, judgement, as well as weakening of logic. These changes are more noticeable in those with MCI as compared to those without it of the same age. While the symptoms of MCI may not interfere with how one goes about his or her daily life, those close to them might notice a change. There is a possibility that the mild cognitive impairment can progress to dementia associated to Alzheimer’s disease (AD) but the impairment can also become better and they become closer to normal cognitive function. Mental symptoms related to MCI include: forgetting information such as important events or appointments, becoming lost in familiar environments, getting overwhelmed by making decisions, etc. Mood symptoms associated with MCI include: depression, anxiety, apathy, and aggression. There is not one exact cause or outcome of MCI. However, it was discovered that some of the causes are closely related to those of Alzheimer’s disease. Some of the risk factors of MCI are increasing age and having ApoE-e4; others include: diabetes, smoking, high blood pressure, elevated cholesterol, and others (Mayo clinic …show more content…
Compared to the normal patients, the MCI and AD subjects displayed some variations in their default mode network, and more specifically in the early phase. When looking at the regions of deactivation, they noticed that the areas of MCI were the same as the control group, just to a smaller degree. There were noticeable differences in the anterior frontal regions between all of the groups: AD, MCI, and control. Regarding the precuneus, MCI and AD greatly differed from the controls, whereas AD and MCI did not differ significantly between each other (Rombouts
It usually involves problem with memory, language, judgement, as well as weakening of logic. These changes are more noticeable in those with MCI as compared to those without it of the same age. While the symptoms of MCI may not interfere with how one goes about his or her daily life, those close to them might notice a change. There is a possibility that the mild cognitive impairment can progress to dementia associated to Alzheimer’s disease (AD) but the impairment can also become better and they become closer to normal cognitive function. Mental symptoms related to MCI include: forgetting information such as important events or appointments, becoming lost in familiar environments, getting overwhelmed by making decisions, etc. Mood symptoms associated with MCI include: depression, anxiety, apathy, and aggression. There is not one exact cause or outcome of MCI. However, it was discovered that some of the causes are closely related to those of Alzheimer’s disease. Some of the risk factors of MCI are increasing age and having ApoE-e4; others include: diabetes, smoking, high blood pressure, elevated cholesterol, and others (Mayo clinic …show more content…
Compared to the normal patients, the MCI and AD subjects displayed some variations in their default mode network, and more specifically in the early phase. When looking at the regions of deactivation, they noticed that the areas of MCI were the same as the control group, just to a smaller degree. There were noticeable differences in the anterior frontal regions between all of the groups: AD, MCI, and control. Regarding the precuneus, MCI and AD greatly differed from the controls, whereas AD and MCI did not differ significantly between each other (Rombouts