Design Variables: Dependent Independent Procedure Analysis: Six Rezende Et Al.

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Authors/citation Study purpose/ Research question Sample/ Participants Design Variables: Dependent Independent Procedures Analysis Results Recommendations Level of Evidence
Mukhopadhyay et al., 2010 This study has two purposes: The first purpose is to see whether a restrictive blood transfusion along with blood conservation system will decrease the amount of pack red blood cell transfusion. The second purpose is to see whether the blood conserving apparatus will conserve hemoglobin level from admission to discharge. Fore every single participant in the control group there are two intervention members. N=80 Participants in the control group and N=170 participants in the intervention group. The original numbers were 106 in the control, six
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Total of 127 trial participants, the control group had 65 members and the active group of the VAMP had 62 members. Prospective randomized controlled trial. Independent variable: The use of VAMP and Dependent preserved hemoglobin and hematocrit (H and H) as well as prevention of blood transfusion. This was a six month long study done in Brazil. They chose three different ICU facilities which had mechanically ventilated ICU adult patients with an arterial line or a central venous catheter lines. Pairwise t-test and Chi-Square test. The VAMP has no effect on transfusion requirement but has some effect on hemoglobin and hematocrit preservation: Control final hct 26.5 vs 29.4 and final control hgb 9.1 vs 9.7 VAMP. This trial failed in the transfusion comparison and that larger studies are needed for better comparison. Level II …show more content…
Intensive care patients requiring arterial line monitoring over 24hrs. 216 participants: 109 test group BCS and 107 comparison group. Prospective Randomized Controlled Trial. Independent variables were blood-saving system venous arterial blood management protection (VAMP) and 3-way stopcock, Dependent variable blood stream microbial contamination, catheter-tip, and intraluminal fluid contamination. This study was done on a 10 bed medical-surgical ICU in Tokushima University Hospital in Japan. Study participants were randomly enrolled into either 3way stopcock control group or blood conserving system (BCS) using venous, arterial blood management system (VAMP-Plus) with a "sealed envelope. Comparison of the blood conservation system and the open system was recorded, a microbial analysis was performed via blood cultures and catheter tip analysis during the catheter removal. 2 group analysis using a Fisher exact test and student t-test Mann-Witney U test In both groups: No difference in colonization (test group 8/109 vs comparator group 11/107 P=0.48), lower intraluminal contamination in the test group (2/109 vs comparator 9/107 P=0.03. There is a correlation between the infection rate and the length of catheter use. Proper line insertion, aseptic line and early removal of the line is needed to prevent infection. Level II

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