Cytosol is the intra-cellular fluid that is present inside the cells. Once the process of eukaryotes starts, the fluid is separated by the cell membrane from the organelles (mitochondrial matrix) and the other contents that float about in the cytosol. Cytosol is the part of the cytoplasm that is not held by any of the organelles in the cell. On the other hand, cytoplasm is the part of the cell which is contained within the entire cell membrane. It is the total content within the cell membrane other than the contents of the nucleus of the cell. All the cell organelles in eukaryotic cells are contained within the cytoplasm. The central, granular mass in the cytoplasm is the endoplasm while the surrounding lucid layer is known as the cell cortex
