The trail of tears had many hardships. One of the hardships were diseases. Diseases were spread quickly. The sanitation was horrible. Another way you could get diseases was from bug bites. Over 4,000 people died from diseases on the way to the settlement. One disease that was spread was typhus. Typhus is a type of rash and a type of disease that was spread really quickly. Many of the Cherokee tribal people died of typhus and other diseases. For example, smallpox was spread quickly. smallpox was one of the most deadly diseases on the trail. The majority of the Native Americans died of smallpox. Since the Native Americans journey was so long the diseases were spread everywhere. Native Americans also caught fevers. Fevers were super high. For
