Daniel Rudman performed an experiment in 1990 revealing the effects of growth hormone in elderly patients. Dr. Rudman hypothesized that administering biosynthetic growth hormone to elderly patients would increase lean body mass, decrease adipose tissue, and thicken the skin. To begin the experiment Dr. Rudman identified a baseline for his twenty-one subjects over six months by noting their IGF-1 levels, insulin like growth hormone factor (an indirect measurement of growth hormone from the liver) and baseline values for body mass, adipose tissue mass, bone density, and skin thickness. After six months of injecting growth hormone Rudman concluded a statistical increase in lean body mass and bone density, and a decrease in adipose tissue. However,
