Moldovan et al. propounded a different method of extraction from pharmaceutical tablets by extraction of with 0.5 M NaOH. Samples were then filtered and transferred to calibrated flasks with double quantity of distilled water [25].
Author selected five Daflon tablets (a mixture of micronized flavonoid glycosides consisting of 450 mg of diosmin and flavonoid extract equivalent to 50 mg of hesperidin) were powdered, and sonicated at 30°C with 90 mL of methanol/DMSO (1:1) for 30 min.
A bioanalytical method involving liquid-liquid extraction of diosmin from plasma samples was developed by Campanero M A et al. Plasma samples were incubated with β- glucuronidase/sulfatase to release diosmetin from its glucuronic acids conjugate. The analytes were
Author selected five Daflon tablets (a mixture of micronized flavonoid glycosides consisting of 450 mg of diosmin and flavonoid extract equivalent to 50 mg of hesperidin) were powdered, and sonicated at 30°C with 90 mL of methanol/DMSO (1:1) for 30 min.
A bioanalytical method involving liquid-liquid extraction of diosmin from plasma samples was developed by Campanero M A et al. Plasma samples were incubated with β- glucuronidase/sulfatase to release diosmetin from its glucuronic acids conjugate. The analytes were