Figure 7. TA flux across membranes prepared with different proportions of AC:Pectin (CP2 and CP3) and DBS concentrations.
Mechanical properties are very important parameters in membranes and coatings. These properties determine the homogeneity, resistance and film forming capacity of the coating. In figure 8 we represent some of the more important mechanical parameters obtained by mean tensile test. Figure 8. Mechanical parameters of the EC:Pectin membranes obtained with CP2 and CP3.
In the membranes prepared without plasticizer, the incorporation of the polysaccharide decreases the resistance and elasticity of the membranes making them more fragile and brittle. Both pectins, CP2 and CP3, produces an increase on the elasticity modulus and …show more content…
We observe similar release rate, independently of the mean size of the pellets, releasing more than the 50% of TA content in 30 minutes and the complete dose in 2-3 hours. Tis results are in accordance with the release obtained in the previous paper (1).
To evaluate the usefulness of membranes as film coating of pellets, we have develop a coating process for this nucleus using a fluid bed apparatus. With this aim, we have made some preliminary studies to select the better experimental conditions to coat the pellets by this technique using coating dispersion with a ratio of EC:Pectin of 3:1. Once the methodological conditions were well stablished, we have coated the pellets with films of different ratio EC:Pectin and also using different coating thickness, calculated as the mean pellets weight gain (MWG) after the coating process.
Figure 11 shows SEM microphotographs of pellet used as nucleus and the coated pellets obtained by fluid bed coating applying different MWG of EC:CP2 coating levels. The SEM images are in accordance with morphological parameters obtained by mean image analysis techniques, observing a decrease in roughness with coating. Image analysis indicatse that uncoated pellets have values of Vr and Vp of 3.72 and 9.95, and after coating (11% MWG) the values of Vr and Vp decreases to 3.49 and 6.28 respectively indicating an increase in the sphericity of the pellets and a decrease
Mechanical properties are very important parameters in membranes and coatings. These properties determine the homogeneity, resistance and film forming capacity of the coating. In figure 8 we represent some of the more important mechanical parameters obtained by mean tensile test. Figure 8. Mechanical parameters of the EC:Pectin membranes obtained with CP2 and CP3.
In the membranes prepared without plasticizer, the incorporation of the polysaccharide decreases the resistance and elasticity of the membranes making them more fragile and brittle. Both pectins, CP2 and CP3, produces an increase on the elasticity modulus and …show more content…
We observe similar release rate, independently of the mean size of the pellets, releasing more than the 50% of TA content in 30 minutes and the complete dose in 2-3 hours. Tis results are in accordance with the release obtained in the previous paper (1).
To evaluate the usefulness of membranes as film coating of pellets, we have develop a coating process for this nucleus using a fluid bed apparatus. With this aim, we have made some preliminary studies to select the better experimental conditions to coat the pellets by this technique using coating dispersion with a ratio of EC:Pectin of 3:1. Once the methodological conditions were well stablished, we have coated the pellets with films of different ratio EC:Pectin and also using different coating thickness, calculated as the mean pellets weight gain (MWG) after the coating process.
Figure 11 shows SEM microphotographs of pellet used as nucleus and the coated pellets obtained by fluid bed coating applying different MWG of EC:CP2 coating levels. The SEM images are in accordance with morphological parameters obtained by mean image analysis techniques, observing a decrease in roughness with coating. Image analysis indicatse that uncoated pellets have values of Vr and Vp of 3.72 and 9.95, and after coating (11% MWG) the values of Vr and Vp decreases to 3.49 and 6.28 respectively indicating an increase in the sphericity of the pellets and a decrease