Cystoid Macular Edema Essay

Pseudophakic cystoid macular edema (PCME), also called Irvine-Gass syndrome, was identified and described for the first time by Irvine-Gass in the 20th century.1 Although the occurrence of PCME has declined with the use of modern surgical techniques, it is still recognized as one of the most common causes of poor visual outcome following cataract surgery.2 The pathogenetic mechanism underlying this syndrome remains unclear, although several factors have been identified potentially capable of influencing the incidence of PCME such as diabetes, a previous diagnosis of epiretinal membrane, uveitis, retinal vein occlusion, retinal detachment repair and capsule rupture with or without vitreous loss.3
However, the most researchers agree that postoperative inflammation seems to be a major cause of PCME because …show more content…
Currently, the AgioVue OCT-A (RTVue XR Avanti; Optovue Inc, Fremont, CA) is the first commercially available OCT device able to provide OCT-A images.
Additionally, OCT-A allows the analysis of the superficial capillary plexus (SCP) and deep capillary plexus (DPC) which can be examined in isolation contrary to FA, that is not able to visualize all relevant vessel layer in the retina. Ref spaide cystoid macula edema.
A new software update released by AngioVue system allows quantification of the percentage of the area occupied by vessel lumens, around the macula in all retinal plexuses, defined as Vascular Density (VD). Ref Florence normative data for vascular density.
Therefore, the aim of this study was to quantify VD at the level of the SCP and DCP using OCT-A. Additionally, we also evaluated the OCT-A appearance of the SCP and DCP in order to compare these findings with those of FA and SD-OCT, in eyes with