Cystic Fibrosis Lab Report

The structure of an enzyme is important because if the structure of the protein is denatured, the protein can not function properly either. Being denatured can be caused by many things but changing the pH or temperature are the main ways to make a protein not to function properly. Any little change in the sequence from protein folding can cause dramatic consequences that might lead to disease or sickness. Cystic Fibrosis is a common disease that affects the whole body, the main and most serious symptom is difficulty with breathing caused by frequent lung infections, Cystic Fibrosis is caused by the dysfunctional gene of the protein CFTR, cystic fibrosis transmembrane conductance regulator. CFTR is required to regulated the sweat, digestive juices, and mucus in the body. with a non dysfunctional gene, the protein is sent to ER and golgi apparatus for processing and then into the cell membrane. …show more content…
People who are prone to delta F508 mutation tend to have more critical symptoms of cystic fibrosis because of the lack of chloride ion transport, needed to control the thin layer of mucus that can be removed by the cilia lining the lungs and organs. The lack of chloride ion transport causes a thick mucus layer that the cilia can not remove, which in result traps bacteria causing disease. The chloride channels are to let chloride out of the epithelium cells. Someone who does that have cystic fibrosis the channels will open a fair amount of times in order to keep it balanced inside and outside of the cells, On the other hand, those with CF the channels do not work properly and the chloride ions build up in the