Cystic fibrosis (CF) is characterized by frequent bacterial infections in the lung that lead to respiratory diseases such as bronchitis and bronchietasis (Konstan et al. 1995). Inflammatory responses in the lungs have been reported to cause damage to the lungs and weakened local defences, thereby preventing the treatment of lung infections (Konstan et al. 1995). However, high doses of ibuprofen are known to reduce swelling, migration and aggregation of neutrophils without increasing the effects of pseudomonas (Konstan and Berger (1993) as cited by Konstan et al (1995)). The journal article by Konstan et al. (1995) has, therefore, aimed to assess the effectiveness of a high dose ibuprofen treatment in lessening the inflammatory response of the
