Recent work done:
Preparation of Fluconazole b-Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation
Hindustan Abdul Ahad and et. al. developed ocuserts containing fluconazole b- cyclodextrin.
Erodible inserts
• The solid inserts absorb the aqueous tear fluid and gradually erode or disintegrate. The drug is slowly leached from the hydrophilic matrix.
• They quickly lose their solid integrity and are squeezed out of the eye with eye movement and blinking.
• Do not have to be removed at the end of their use.
Three types :
1. Lacriserts
2. Sodi
3. Minidisc
LACRISERTS
• Sterile rod shaped device made up of hydroxyl propyl cellulose without any preservative.
• For the treatment of dry eye syndromes.
• It weighs 5 mg and measures 1.27 mm in diameter with a length of 3.5 mm.
• It is inserted into the inferior fornix.
SODI
• Soluble ocular drug inserts.
• Small oval wafer.
• Sterile thin film of oval shape.
• Weighs 15-16 mg.
• Use – glaucoma.
• Advantage – Single application.
Minidisc
• Countered disc with a convex front and a concave back surface.
• Diameter – 4 to 5 mm.
Composition
• Silicone based prepolymer-alpha-w-dis (4-methacryloxy)-butyl poly di methyl siloxane. (M2DX)
• …show more content…
Myopia progression is fastest in children between the ages of six and sixteen. The ever increasing demands on children's eyesight today, from not only books and TV, but computers, mobile phones and gaming devices has lead to a dramatic increase in short-sightedness in the last 20 years. Whilst myopia is inherited, (the risk of it developing is increased if both parents are short sighted), technology is believed to be having catastrophic consequences on children's eyesight. The opportunity to fit children with this new type of contact lens, not only means that children don't have to wear glasses, something most children would appreciate, but also that their progression of myopia is
Preparation of Fluconazole b-Cyclodextrin Complex Ocuserts: In Vitro and In Vivo Evaluation
Hindustan Abdul Ahad and et. al. developed ocuserts containing fluconazole b- cyclodextrin.
Erodible inserts
• The solid inserts absorb the aqueous tear fluid and gradually erode or disintegrate. The drug is slowly leached from the hydrophilic matrix.
• They quickly lose their solid integrity and are squeezed out of the eye with eye movement and blinking.
• Do not have to be removed at the end of their use.
Three types :
1. Lacriserts
2. Sodi
3. Minidisc
LACRISERTS
• Sterile rod shaped device made up of hydroxyl propyl cellulose without any preservative.
• For the treatment of dry eye syndromes.
• It weighs 5 mg and measures 1.27 mm in diameter with a length of 3.5 mm.
• It is inserted into the inferior fornix.
SODI
• Soluble ocular drug inserts.
• Small oval wafer.
• Sterile thin film of oval shape.
• Weighs 15-16 mg.
• Use – glaucoma.
• Advantage – Single application.
Minidisc
• Countered disc with a convex front and a concave back surface.
• Diameter – 4 to 5 mm.
Composition
• Silicone based prepolymer-alpha-w-dis (4-methacryloxy)-butyl poly di methyl siloxane. (M2DX)
• …show more content…
Myopia progression is fastest in children between the ages of six and sixteen. The ever increasing demands on children's eyesight today, from not only books and TV, but computers, mobile phones and gaming devices has lead to a dramatic increase in short-sightedness in the last 20 years. Whilst myopia is inherited, (the risk of it developing is increased if both parents are short sighted), technology is believed to be having catastrophic consequences on children's eyesight. The opportunity to fit children with this new type of contact lens, not only means that children don't have to wear glasses, something most children would appreciate, but also that their progression of myopia is