Crohn's Disease Research Paper

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Crohn’s disease (CD) is a chronic inflammatory bowel disease (IBD) characterized by inflammation of the digestive or gastrointestinal tract. Crohn’s can affect any part of the gastrointestinal tract from the mouth to the anus, but is more commonly found at the end of the small intestine where it joins the beginning of the large intestine (or colon). It can also affect an individual’s eyes, skin, and joints. Interestingly, the incidence and prevalence of Crohn’s disease is high in industrialized countries but fairly low in developing countries. However, it has been recently found that as industrial progressions have risen in some developing countries (like Asia and Africa), the occurrence of CD has also risen. Not only does CD appear to be more …show more content…
For example, mild symptoms may include frequent diarrhea and abdominal pain but individuals can walk and eat normally. With mild symptoms there are no signs of dehydration, high fever, abdominal tenderness, painful mass, intestinal obstruction, or weight loss of more than ten percent. Moderate to severe symptoms become a little more obvious with frequent diarrhea, abdominal pain or tenderness, fever, significant weight loss, and significant anemia. Anemia can also cause fatigue, shortness of breath, as well as dizziness and headaches. Very severe symptoms include persistent symptoms despite appropriate treatment for moderate to severe Crohn’s, but may also experience high fever, more severe weight loss, persistent vomiting, and evidence of intestinal obstruction such as a blockage or …show more content…
Incidence of inflammatory bowel disease in Asia is estimated to be less than 5 per 100,000 people. These increases are mostly due to rapid urbanization and industrialization. Industrialization is associated with changes in diet, antibiotic use, hygiene status, microbial exposures, and pollution. Of the Chinese population, there seems to be an increasing trend of Crohn’s disease in the Singapore Chinese population. Countries with the highest incidences of CD involve Turkey, Lebanon, and South Korea. On the other hand, Lebanon, Japan, and South Korea rank as the first three countries with the highest prevalence. Also experiencing increasingly higher rates of CD in the last three decades are South Korea, Japan, and Hong Kong. Unfortunately, not enough research and development have been done to crunch the economic costs of Crohn’s disease in Asian countries however, with incidence and prevalence rates increasing, future economic research is

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